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Fundamental tools for understanding and applying the medical literature and making clinical diagnoses.
 
Core Topics in Evidence-Based Medicine
 
 
Learn how to recognize, classify, and prioritize important patient or policy problems.
Construct clinical questions that facilitate an efficient search for evidence.
Gather important and convincing evidence from high-quality repositories of the health literature.
Systematically check best available evidence for indications of validity, importance, and usefulness.
Interpret the applicability of evidence to specific problems, given patient preferences and values.
 
     
 
In Practice
 
 
Otitis Media, Child
A 12-month-old boy is brought to the clinic by his parents for evaluation of a possible ear... Continue reading
 
     
 
August 2014 | Featured on JAMAevidence
 
 
JAMAevidence PODCAST  

David L. Simel, MD, MHS, discusses the clinical examination for abnormal central venous pressure. (7:05)

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New Chapter from The Rational Clinical Examination

Sleep Apnea
Evidence-Based Medicine Oral History 

Watch the new video featuring interviews of the leaders of the Evidence-based medicine (EBM) movement.
 
     
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Custom Syllabus
 
 
Custom Syllabus is an education tool that allows instructors and learners to create courses and topics based on the content of the JAMAevidence web site, as well as other materials. Find out more
 
     
 
My JAMAevidence
 
 
JAMAevidence subscribers have access to features such as saved images and tables, saved worksheets and question wizards, and bookmarking.
 
     
 
Users' Guides to the Medical Literature
 
 
Users' Guides to the Medical Literature
A Manual for Evidence-Based Clinical Practice, 2nd Edition
FEATURED
Surrogate Outcomes

You are an internist treating a 56-year-old woman with type 2 diabetes . . . Continue reading
 
     
 
The Rational Clinical Examination
 
 
The Rational Clinical Examination
Evidence-Based Clinical Diagnosis
FEATURED
Myasthenia Gravis

Myasthenia gravis is a rare disease. The prevalence in the United States . . . Continue reading
 
     
 
Care at the Close of Life
 
 
Care at the Close of Life
Evidence and Experience
FEATURED
Agitation and Delirium at the End of Life: “We Couldn’t Manage Him”

Mr L was a 59-year-old man with metastatic non–small cell lung cancer . . . Continue reading
 
     
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