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Fundamental tools for understanding and applying the medical literature and making clinical diagnoses.
Core Topics in Evidence-Based Medicine
Learn how to recognize, classify, and prioritize important patient or policy problems.
Construct clinical questions that facilitate an efficient search for evidence.
Gather important and convincing evidence from high-quality repositories of the health literature.
Systematically check best available evidence for indications of validity, importance, and usefulness.
Interpret the applicability of evidence to specific problems, given patient preferences and values.
In Practice
A 68-year-old woman calls for an urgent appointment before a midwinter trip to visit with her... Continue reading
September 2014 | Featured on JAMAevidence
JAMAevidence PODCAST  

Lewis M. Cohen, MD, discusses practical considerations in dialysis withdrawal. (6:45)

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New Education Guide from The Rational Clinical Examination

Severe Upper Gastrointestinal Bleed
Evidence-Based Medicine Oral History 

Watch the new video featuring interviews of the leaders of the Evidence-based medicine (EBM) movement.
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Custom Syllabus
Custom Syllabus is an education tool that allows instructors and learners to create courses and topics based on the content of the JAMAevidence web site, as well as other materials. Find out more
My JAMAevidence
JAMAevidence subscribers have access to features such as saved images and tables, saved worksheets and question wizards, and bookmarking.
Users' Guides to the Medical Literature
Users' Guides to the Medical Literature
A Manual for Evidence-Based Clinical Practice, 2nd Edition
Surrogate Outcomes

You are an internist treating a 56-year-old woman with type 2 diabetes . . . Continue reading
The Rational Clinical Examination
The Rational Clinical Examination
Evidence-Based Clinical Diagnosis
Myasthenia Gravis

Myasthenia gravis is a rare disease. The prevalence in the United States . . . Continue reading
Care at the Close of Life
Care at the Close of Life
Evidence and Experience
Agitation and Delirium at the End of Life: “We Couldn’t Manage Him”

Mr L was a 59-year-old man with metastatic non–small cell lung cancer . . . Continue reading
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