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Care at the Close of Life: Evidence and Experience
Stephen J. McPhee, Margaret A. Winker, Michael W. Rabow, Steven Z. Pantilat, Amy J. Markowitz
Part B Symptom Management
Chapter 9. Palliative Management of Fatigue at the Close of Life: “It Feels Like My Body Is Just Worn Out”
Sriram Yennurajalingam, MD, Eduardo Bruera, MD
Finally, in an open-label pilot study of 27 patients with advanced cancer and cancer pain,...

Topics Discussed: adrenal corticosteroids, cancer fatigue, exercise, fatigue, observational studies, psychostimulant, randomized controlled trials, summarizing the evidence

Excerpt: "Until recently, energy conservation was the most frequently recommended treatment for fatigue in palliative care.103 However, prospective cohort and randomized controlled trials have shown that the risk of energy conservation is deconditioning, creating the potential for a vicious cycle of fatigue and further deconditioning, subsequently leading to disability.104..."
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