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The Rational Clinical Examination
David L. Simel, Drummond Rennie
Chronic Wound Infection
David L. Simel
Make the Diagnosis: Infection of Chronic Wounds


Topics Discussed: levine technique, make the diagnosis, prior probability, soft tissue mass biopsy

Excerpt: "Chronic wounds are those that have not undergone an orderly healing process. This imprecise definition requires judgment about when a wound has become chronic. Not all chronic wounds are infected. Among patients with chronic wounds evaluated in the highest-quality clinical studies, the prevalence of infected wounds was 45% (95% CI, 32%-58%). Because of the heterogeneity (I2=82%) that is seen through the broad CI, a useful way to remember this is that about half of chronic wounds will be infected, with a range of about one-third to two-thirds.1..."
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