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The Rational Clinical Examination
David L. Simel, Drummond Rennie
Pulmonary Embolus
Sanjeev Chunilal, Ginsberg Jeff, Phil Wells
Computed Tomography Angiography

Topics Discussed: enzyme-linked immunosorbent assay, fibrin d-dimer assay, pulmonary embolism

Excerpt: "Despite recent advances in the visualization of pulmonary arteries with the advent of spiral CT, there are no well-designed clinical outcome studies validating its role as a standalone test in the treatment of unselected patients with suspected pulmonary embolism. Newer advances in this technology, with the advent of multidetector modalities, may improve scan acquisition times and image quality. At present, although spiral CT continues to improve in its diagnostic accuracy for pulmonary embolism, a negative spiral CT result by itself is still not sufficient to reliably exclude pulmonary embolism.9..."
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