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The Rational Clinical Examination
David L. Simel, Drummond Rennie
Myasthenia Gravis
Katalin Scherer, Richard S. Bedlack, David L. Simel
Clinical Scenarios


Topics Discussed: diplopia, eyelid ptosis, myasthenia gravis

Excerpt: "A 45-year-old man has a 2-month history of fluctuating double vision, a droopy right eye that improves with rest, and a complaint that food gets stuck halfway down. Your examination confirms severe right eyelid ptosis that dramatically improves with rest. His right eye adduction and up gaze are markedly impaired. The left eye demonstrates complete horizontal ophthalmoplegia. The limb muscle strength and reflexes are normal. You wonder whether there is an accurate and clinically useful bedside test to help confirm the diagnosis of myasthenia gravis...."
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