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The Rational Clinical Examination
David L. Simel, Drummond Rennie
Compliance and Medication Adherence
Hayden B. Bosworth, Amy Rosenthal

Sections:  Clinical Scenario, Updated Summary on Compliance and Medication Adherence, Updated Literature Search, New Findings, Improvements in the Data Presented in the Original Publication, Changes in the Reference Standard, Results of Literature Review, Evidence From Guidelines, Clinical Scenario—Resolution, References for the Update

Topics Discussed: adherence, medication adherence, nonadherent, noncompliance with treatment, patient compliance

Excerpt: "A 65-year-old woman prescribed a diuretic and an angiotensin-converting enzyme inhibitor continues to have inadequate blood pressure control. She volunteers that she takes her medicines exactly as instructed on her bottles but did not bring the bottles with her. You are considering adding another antihypertensive medication, but she is already taking 2 other medications for diabetes. Can you be confident that she is taking her medications as prescribed? Is there a way to get a better history of her medication adherence?..."
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