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Users' Guides to the Medical Literature
Guyatt G, Rennie D, Meade MO, Cook DJ
Part G Moving from Evidence to Action
Chapter 22.1. Economic Analysis
Michael Drummond, Ron Goeree, Paul Moayyedi, Mitch Levine
Clinical Scenario


Topics Discussed: application of economic analysis (cost-effectiveness), cost effectiveness, dyspepsia, economic analysis (cost-effectiveness), endoscopy, helicobacter pylori

Excerpt: "You are a gastroenterologist on the staff of a large community hospital. Your chief of medicine knows your interest in evidence-based medicine, and she asks you to help her solve a problem. There is considerable pressure on the endoscopy service to provide more colonoscopy screening to reduce colorectal cancer mortality, but no funds are available to increase endoscopy facilities. Approximately 50% of the workload is devoted to upper gastrointestinal endoscopy for patients with dyspepsia. One possibility is to reduce upper gastrointestinal endoscopy demand by providing a Helicobacter pylori test and treat service as the preferential management strategy for patients younger than 55 years with dyspepsia without alarm symptoms. This strategy involves giving patients a noninvasive test for H pylori (eg, a serology test or urea breath test), treating patients with positive results with antibiotic therapy, and reassuring patients with negative results that they are unlikely to have peptic ulcer disease...."
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