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Users' Guides to the Medical Literature
Guyatt G, Rennie D, Meade MO, Cook DJ
Part A The Foundations
Chapter 3. What Is the Question?
Gordon Guyatt, Maureen O. Meade, Scott Richardson, Roman Jaeschke

Sections:  Three Ways to Use the Medical Literature, Clarifying Your Question, Defining the Question: Conclusion, References

Topics Discussed: asking clinical questions

Excerpt: "Consider a medical student, early in her training, seeing a patient with newly diagnosed diabetes mellitus. She will ask questions such as the following: What is type 2 diabetes mellitus? Why does this patient have polyuria? Why does this patient have numbness and pain in his legs? What treatment options are available? These questions address normal human physiology and the pathophysiology associated with a medical condition.A general internist scanning the September/October 2005 ACP Journal Club ( comes across the following articles: "Intensive Insulin-Glucose Infusion Regimens With Long-Term or Standard Glucose Control Did Not Differ for Reducing Mortality in Type 2 Diabetes Mellitus and MI,"1 and "Review: Mixed Signals From Trials Concerning Pharmacologic Prevention of Type 2 Diabetes Mellitus."2..."
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