Users' Guides to the Medical Literature
Guyatt G, Rennie D, Meade MO, Cook DJ
Part B Therapy
Chapter 11.3. Dealing With Misleading Presentations of Clinical Trial Results
Victor Montori, John Ioannidis, Roman Jaeschke, P. J. Devereaux, Holger Schünemann, Mohit Bhandari, Gordon Guyatt
Consider, for example, 2 systematic reviews published in 2001 summarizing randomized trials...
Topics Discussed:
amitriptyline, angiotensin receptor antagonists, angiotensin-converting enzyme inhibitors, antibiotics, antipsychotic agents, approach to medical literature, clinical trials, coronary arteriosclerosis, diabetic nephropathy, diuretics, equivalence studies, fluid resuscitation, haloperidol, hiv, hypertension, interpretation of results, intervention/exposure, misleading results, research outcome, sinusitis, stroke prevention, systematic reviews, therapeutic equivalency, treatment effect, understanding the results, validity of evidence
Excerpt:
"The discussion (and to some extent the abstracts, introduction,
and the conclusion section of structured abstracts) often offers
inferences that differ from those a dispassionate reader would draw
from the methods and results.7..."
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