Users' Guides to the Medical Literature
Guyatt G, Rennie D, Meade MO, Cook DJ
Part B Therapy
Chapter 11.1. Applying Results to Individual Patients
Antonio L. Dans, Leonila F. Dans, Gordon Guyatt
Clinical Resolution
Topics Discussed:
clinical decision making, myocardial infarction, streptokinase, thrombolytic therapy
Excerpt:
"What should we recommend regarding use of thrombolytic agents for
the Filipino patient admitted to the hospital with acute MI? In summary,
there is no reason to believe that Filipinos will have a different
response to treatment with thrombolytic agents under ideal conditions.
Patient adherence will not be an important issue because the
drug is given intravenously as a single dose. The technical requirements
for administration are often (but not always) available, and when
they are not, the risks of thrombolytic administration
may outweigh the benefits. Fortunately, in this hospital, minimum
technical requirements were met...."
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