JAMAevidence

Fundamental tools for understanding and applying the medical literature and making clinical diagnoses.

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Core Topics in Evidence-Based Medicine

	Learn how to recognize, classify, and prioritize important patient or policy problems.
	Construct clinical questions that facilitate an efficient search for evidence.
	Gather important and convincing evidence from high-quality repositories of the health literature.
	Systematically check best available evidence for indications of validity, importance, and usefulness.
	Interpret the applicability of evidence to specific problems, given patient preferences and values.

	In Practice
	From The Rational Clinical Examination Ascites A 48-year-old man became intoxicated and fell down several steps. He presents to the emergency... Continue reading See also: *Make the Diagnosis: Ascites*

	June 2013 \| Featured on JAMAevidence
	JAMAevidence PODCAST Toshi A. Furukawa, MD, PhD, discusses diagnostic tests. (16:10) Download this Podcast \| View All New Education Guide From The Rational Clinical Examination Delirium Updates to the Glossary May 2013: AST:ALT ratio (AAR); AST:platelet ratio index (APRI); Bonacini cirrhosis discriminant score (CDS); Facial telangiectasia; Lok index; Palmar erythema; Spider nevi Click to view the full JAMAevidence Glossary or only the Care at the Close of Life Glossary. Top searched terms in the glossary Bayesian analysis Fixed-effects models Heterogeneity Meta-regression analysis Random-effects model CALCULATOR Risk Increase Nomogram

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	Custom Syllabus
	Custom Syllabus is an education tool that allows instructors and learners to create courses and topics based on the content of the JAMAevidence web site, as well as other materials. Find out more

	My JAMAevidence
	JAMAevidence subscribers have access to features such as saved images and tables, saved worksheets and question wizards, and bookmarking.

Users' Guides to the Medical Literature

Users' Guides to the Medical Literature
A Manual for Evidence-Based Clinical Practice, 2nd Edition

FEATURED
Applying Results to Individual Patients

You are the attending internist on duty when a 40-year-old history professor presents to the emergency department... Continue reading

The Rational Clinical Examination

The Rational Clinical Examination
Evidence-Based Clinical Diagnosis

FEATURED
Acute Cholecystitis

No single clinical finding, or known combination of clinical history and physical examination findings, efficiently establishes a diagnosis of... Continue reading

Care at the Close of Life

Care at the Close of Life
Evidence and Experience

FEATURED
Managing an Acute Pain Crisis in a Patient With Advanced Cancer: "This Is as Much of a Crisis as a Code"

Mr X is a 33-year-old man with a 4-year history of metastatic mucinous adenocarcinoma of the appendix... Continue reading

	Education Guides
	The Rational Clinical Examination Education Guide: Splenomegaly View Online Slideshow \| Download PowerPoint View all Education Guides View sample slideshow from Users’ Guides to the Medical Literature View sample slideshow from The Rational Clinical Examination View sample slideshow from Care at the Close of Life

	This Week's JAMA
	JAMA June 18, 2013 • This Week in JAMA • Building Trust in the Power of “Big Data” Research to Serve the Public Good “Big Data” Research to Serve the Public Good • Defining “Term” Pregnancy Recommendations From the Defining “Term” Pregnancy Workgroup Defining “Term” Pregnancy • Spinal Injection Therapy for Low Back Pain Spinal Injection Therapy for Low Back Pain