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Fundamental tools for understanding and applying the medical literature and making clinical diagnoses.
Core Topics in Evidence-Based Medicine
Learn how to recognize, classify, and prioritize important patient or policy problems.
Construct clinical questions that facilitate an efficient search for evidence.
Gather important and convincing evidence from high-quality repositories of the health literature.
Systematically check best available evidence for indications of validity, importance, and usefulness.
Interpret the applicability of evidence to specific problems, given patient preferences and values.
In Practice
Carpal Tunnel Syndrome
Your 50-year-old secretary complains to you that she cannot complete your clinic notes on the... Continue reading
April 2014 | Featured on JAMAevidence
JAMAevidence PODCAST  

Ann C. Hurley, RN, DNSc, discusses Alzheimer disease. (15:06)

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New Chapter from The Rational Clinical Examination

Ectopic Pregnancy
Evidence-Based Medicine Oral History 

Watch the new video featuring interviews of the leaders of the Evidence-based medicine (EBM) movement.
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Custom Syllabus
Custom Syllabus is an education tool that allows instructors and learners to create courses and topics based on the content of the JAMAevidence web site, as well as other materials. Find out more
My JAMAevidence
JAMAevidence subscribers have access to features such as saved images and tables, saved worksheets and question wizards, and bookmarking.
Users' Guides to the Medical Literature
Users' Guides to the Medical Literature
A Manual for Evidence-Based Clinical Practice, 2nd Edition
Example Numbers Needed to Treat

Evidence-based practice requires that clinicians summarize the benefits and risks of treatment of patients . . . Continue reading
The Rational Clinical Examination
The Rational Clinical Examination
Evidence-Based Clinical Diagnosis
Irritable Bowel Syndrome

During a lifetime, everyone experiences lower gastrointestinal tract symptoms . . . Continue reading
Care at the Close of Life
Care at the Close of Life
Evidence and Experience
Palliative Care for Patients with Head and Neck Cancer

Mr K is a 57-year-old financial analyst with a long history of precancerous and cancerous oral lesions . . . Continue reading
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